31 - 35 Pharmacology SBAs for the Primary FRCA

Last updated on Apr 4, 2024

Question 31

You're feeling pretty pleased with yourself for correctly answering your consultant's question on how metaraminol works, when she starts asking about adrenoceptors in other organs.

Which of the following is false?

Beta-2 receptor stimulation in the liver increases glycogenesis
Beta-1 receptor stimulation in the juxtaglomerular apparatus increases renin secretion
GI alpha-1 receptor stimulation leads to sphincter contraction
Alpha-2 receptor stimulation will encourage platelet aggregation
Alpha-1 stimulation in the pancreas will inhibit insulin and glucagon secretion

Answer

Beta-2 receptor stimulation in the liver increases glycogenesis

Beta-2 receptor stimulation in the liver increases glycogenolysis to increase blood glucose concentration.

All of the others are true.

Metaraminol stimulates vascular alpha-1 receptors, making it a pure vasopressor.