Antimuscarinics

  • Demonstrate an awareness of the anatomy of the parasympathetic nervous system and the function of the muscarinic acetylcholine receptor subtypes
  • Recall the pertinent pharmacokinetic and pharmacological properties of Atropine and Glycopyrrolate
  • Compare and contrast the properties of these drugs and their clinical uses in anaesthetic practice
  • Use this knowledge and understanding to select an appropriate antimuscarinic agent in various clinical scenarios

Atropine

Glycopyrrolate

Quiz

2
Created on By Anaestheasier

Antimuscarinics

1 / 15

Which of the following statements regarding Atropine is true?

2 / 15

Which statement about Glycopyrrolate is incorrect?

3 / 15

Which of the following drugs does not have antagonistic effects at muscarinic receptors?

4 / 15

You are anaesthetising a 56-year-old male undergoing the last stage of his occular globe reconstruction. During the surgery, you notice he becomes severely bradycardic at 26bpm. You tell the surgeon to stop immediately and you call for help immediately. Which of the following would be appropriate treatments (+/- CPR to circulate the drug)?

5 / 15

Chronotropic effects of Glycopyyrolate are predominantly mediated by antagonism of which receptor?

6 / 15

A 23-year-old lady is undergoing a diagnostic laparoscopy. Upon insufflation of the abdomen, the patient’s heart rate drops to 20bpm. You call for help and tell the surgeon to stop insufflating. While help is coming, you give 600mcg (1ml) of Atropine IV with chest compressions as the patient is now asystolic. Which statement regarding atropine is incorrect?

7 / 15

Which receptor is responsible for the vagal effect on the heart?

8 / 15

You are preparing emergency drugs ready for a paediatric case. The child is 3-year-old Alfie who is undergoing an orchidopexy for an undescended testicle. He weighs 16kg.

Atropine dose for children in 10-20mcg/kg and your hospital supplies ampoules of 600mcg/ml. What is the maximum volume of atropine that would be appropriate to administer should it be required?

9 / 15

Which of the following anticholinergic drugs does not act on the muscarinic receptor.

10 / 15

Which of the following statements regarding the heart is incorrect?

11 / 15

Which statement below regarding the autonomic system is correct?

12 / 15

Which of the following is not a side-effect of Atropine?

13 / 15

Which of the following receptors are predominant at parasympathetic ganglions?

14 / 15

Which of the following statements regarding the Autonomic Nervous System is incorrect?

15 / 15

Which of the following Cranial Nerves does not carry Parasympathetic fibres?

Your score is

The average score is 63%

0%

Summary PDF

All of our summary PDFs in one bundle